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Vancomycin
Resistant Enterococci
(VRE)
Patient Education Reference 160 (PDF Format)

VRE: Description and Epidemiology
VRE: The Facts
For More Information
John Hopkins Standard Teaching Plan for VRE
What does antibiotic resistance mean?
Germs called bacteria may cause infections. Antibiotics
are drugs used to treat infections caused by bacteria. Sometimes
these drugs will no longer kill the germs. This is called antibiotic
drug resistance.
What are enterococci?
Enterococci are germs that are normally in the bowel. Enterococci
can go to other parts of the body and cause an infection. Vancomycin
is a drug (antibiotic) used to treat infections caused by enterococci.
If a germ is resistant to vancomycin, treatment with vancomycin will
not get rid of the infection. These germs are called "Vancomycin
Resistant Enterococci" or VRE for short.
What is infection vs. colonization?
An infection means that germs are in or on the body and make you
sick which results in signs and symptoms such as fever, pus from a
wound or a high white blood cell count. Germs can also be in the body,
but not make you sick. This is called colonization. People who are
colonized will have no signs and symptoms. They will feel fine. VRE
can cause infection and colonization.
What are risk factors for getting VRE?
Patients at most risk for getting VRE are those who have been in
an intensive care unit, sick with a long term illness, have been on many
different types of antibiotics, have had major surgery or an organ
or bone marrow transplant.
How do I know if I have VRE?
If your doctor wants to test you for VRE, a sample of your blood,
urine or stool is sent to the lab to see if VRE is present. This
test is called a culture. If there is VRE in the sample, the culture
is positive. This means that you have VRE in your body.
What will this mean for my hospital care?
All patients who have a positive culture for VRE are placed
in isolation. Isolation is used to keep from spreading VRE to other
patients. There will be a cart outside the room to hold
supplies. A card will be placed on the door to alert everyone what
precaustions are needed to enter the room. Hospital staff will wear
gowns and gloves to care for you. Visitors should report to the
nurses station for directions on what to do to enter your room. All
of these steps are to keep germs from spreading.
Am I contagious?
VRE can not be spread by coughing or sneezing. VRE can be on
your hands, and can get there from your stool or urine. You can
then spread it to anything you touch if you do not clean your hands.
Hands must be washed with soap and water for ten seconds or cleaned
using a waterless hand cleaner. Handwashing after using the toilet is
very important. In some cases VRE will go away for a time, but then it
may come back. Cultures can be taken to see if it goes away.
Unfortunately, eveb after VRE gies away, as soon as you require
antibiotics again, VRE usually comes back. For this reason, HEIC does
not recommend routinely re-culturing to take you out of isolation.
What will happen when I go home?
At home, in most cases, you only need to use good handwashing.
Healthy family members are not likely to get VRE. Based on
your discharge needs, instructions will be given by the nursing
staff.
What will happen if I'm back in the hospital or come to clinic?
The Johns Hopkins Hospital wants to prevent the spread of VRE.
If you come back into the hospital, you will be placed in isolation
again. When you go to doctor's offices or to hospital clinic appointments,
you should tell the doctors and nurses that you have VRE, so they
can take steps to avoid spreading it to others.
Will I ever be rid of VRE?
Over time your normal bowel organisms may take the place of VRE.
You will no longer be isolated when three stool or rectal swabs
taken a week apart are negative for VRE.
Where can I get more information about VRE?
- Talk to your doctor or nurse.
- Call The Johns Hopkins Hospital: Hospital Epidemiology/ Infection Control Department
at 410-955-8384.
- Review the centers for Disease Control and Prevention (CDC) website
http://www.cdc.gov.
Developed by the Johns Hopkins Hospital: Hospital Epidemiology and Infection Control Department.
Copyright 1998 The Johns Hopkins Hospital Revised July 2003
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