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May stop additional isolation when:
Lesion stops draining
Symptoms
Acute or insidious onset, intermittent or irregular fever, headache,
weakness, profuse sweating, chills, arthralgia, depression, weight
loss, and generalized aching.
Comments:
There is a risk of infection for laboratory personnel handling samples.
Label microbiology specimens “brucellosis” so that samples may be handled
appropriately.
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Incubation Period
Range 5 days to 60 days. 1-2 months common. 1- 40 days if inhaled.
Period of Communicability
No person to person transmission
Cohort (Inf. with Inf./Exp. with Exp./Non-Exp. with Non-Exp.)
Not Required
Transport Issues
None
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Who’s susceptible
General
Who’s exposed
Contact with infected animal tissues. Consumption of contaminated dairy
products. Accidental exposure to vaccine strain. Exposure to laboratory
(microbiologic) samples
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Exclusion of symptomatic personnel from duty
Yes, until fit to work.
Exclusion of exposed susceptible personnel from duty
Not required
Isolation of exposed susceptible asymptomatic patients
Not required
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Prophylaxis for exposed
Laboratory exposures: Doxycycline 100 mg PO BID and Rifampin 600-900 mg
PO once daily for 21 days. For conjunctival exposure - 4-6 weeks prophylaxis.
Treatment for ill
Doxycycline 100 mg PO BID and Rifampin 600-900 mg PO/IV qd OR, OR
Ciprofloxin 500 IV BID PLUS Rifampin 600-900mg PO/IV qd OR Ceftriaxone
1-2gms IV BID PLUS Rifampin 600-900mg PO/IV qd (for CNS disease). ALL
for 6 weeks.
Military/Institutional Populations Special Issues
Could be used as a biowarefare agent
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